Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Specificity and Use
RANBPM antibody was raised against synthetic peptide
Western blot Analysis: RanBPM can be detected at 1/1000 in rat, mouse and human brain. Immunohistochemistry: 1:50 and 1:500 dilution of Cat. # AB15301 was tested on human normal, tumor tissue and tonsil tissue.
RANBP9 Antibody, BPM90 Antibody, RAN binding protein 9 Antibody, Ran-binding protein 9 Antibody, RANBPM Antibody, BPM-L Antibody, Ran-binding protein M Antibody, RanBP7 Antibody
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation.