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The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.
Gene Name: | RAN binding protein 17 |
Synonyms: | RANBP17, Ran-binding protein 17, RAN binding protein 17 |
Target Sequences: | NM_022897 NP_075048.1 Q9H2T7 |
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