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RAB27A / RAB27 belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Gene Name: | RAB27A, member RAS oncogene family |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , RAS oncogene |
Synonyms: | RAB27A, GS2, GTP-binding protein Ram, HsT18676, RAB27, Ras-related protein Rab-27A, Rab-27, RAM |
Target Sequences: | NM_004580 NP_004571.2 P51159 |
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