Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Western blot (1:500)
Synthetic peptide corresponding to aa430-733.
Recognizes human Protein Tyrosine Phosphatase, Receptor Type Z1, which is expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain.
Suitable for use in ELISA and Western Blot. Western Blot: 1:500.
PBS, pH 7.2, 0.02% Sodium Azide
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
PTP zeta 1, a R5 receptor protein tyrosine phosphatase, is a central nervous system specific receptor phosphatase that has been shown to affect axon guidance, cell interactions, maintenance and plasticity of synaptic structure and functions, and neurite outgrowth during nervous tissue histogenesis. PTP Zeta has both transmembrane and cytosolic isoforms.