Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Protein G purified
Specificity and Use
PTPN7 / HEPTP antibody was raised against synthetic peptide from human PTPN7. Percent identity by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (94%); Marmoset, Mouse, Rat, Hamster, Panda, Dog, Horse (88%); Elephant, Bovine (81%).
KLH conjugated synthetic peptide comprising amino acids 22 - 37 [MTQPPPEKTPAKKHVR] of the human protein tyrosine phosphatase non-receptor type 7 (PTPN7) protein.
PBS, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
PTPN7 / HEPTP is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities.