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Anti-PTK2B / PYK2 Antibody (phospho-Tyr580) LS-C17531

Catalog Size Price
LS-C17531-10 10 blot Unavailable

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Anti-PTK2B / PYK2 Antibody (aa704-941, Biotin) LS-C685731
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100% Guaranteed
Rabbit Polyclonal to Human PTK2B / PYK2
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human PTK2B / PYK2
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot

Specificity and Use

PTK2B / PYK2 antibody was raised against synthetic phosphopeptide derived from the region of human Pyk2 that contains tyrosine 580. The sequence is conserved in mouse and rat.
pTyr580
Reactivity: Human Pyk2. Mouse and rat (100% homologous) Pyk2 have not been tested, but are expected to react.
Suitable for use in Western blotting applications. Previous lots of this antibody have been used in immunostaining. The current lot has not yet been validated for this application. For Western blotting applications, we recommend using the antibody at a 1:1000 dilution. Positive control: Chicken embryo fibroblasts (CEFs) expressing human Pyk2 protein and plated on fibronectin.

Packaging

PBS (without Mg2+, Ca2+), 1 mg/ml BSA (IgG, protease free), pH 7.2, 0.1% sodium azide, 50% glycerol.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About PTK2B / PYK2

Q14289 NM_004103 NP_004094.3

PTK2B Antibody, CADTK Antibody, CAKB Antibody, Cell adhesion kinase beta Antibody, FADK 2 Antibody, FADK2 Antibody, Focal adhesion kinase 2 Antibody, FRNK Antibody, FAK2 Antibody, Proline-rich tyrosine kinase 2 Antibody, Protein-tyrosine kinase 2-beta Antibody, Protein kinase B Antibody, Protein tyrosine kinase 2 beta Antibody, PYK2 Antibody, RAFTK Antibody, CAK-beta Antibody, PKB Antibody, PTK Antibody

Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation.

Requested From: 
Date Requested: 5/20/2018

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