Ammonium sulfate precipitation
PTHR2 / PTH2R antibody was raised against synthetic peptide corresponding to the amino acids 99 - 116 of the native molecule. ( EXTRACELLULAR DOMAIN 1 ).
The extracellular domain 1 of parathyroid hormone receptor 2. A member of the G-protein coupled receptor family, particularly abundant in the brain and pancreas. It may be responsible for PTH effects in a number of physiological systems and may play a significant role in pancreatic function. Binds parathyroid hormone, but shows very low affinity for PTHrP. This molecule is expressed in only a few tissues, and its structure and physiologic significance are poorly characterized. Type 2 receptor, is coupled to adenylyl cyclase, ligand binding induces a rise in intracellular concentration of cyclic AMP. PTH-Rec 2 (99-116) 100% PTH-Rec 1 (63-82) 0.06% PTH-Rec 1 (562-580) 0.4%.
Store at 4°C or -20°C. Avoid freeze-thaw cycles.