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Anti-PTGER2 / EP2 Antibody (Extracellular Domain) IHC-plus™ LS-A4202

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Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
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Rabbit Polyclonal to Human PTGER2 / EP2
Human, Mouse, Bat, Bovine, Pig
IHC - Paraffin, ELISA
Unconjugated

Details

Human PTGER2 / EP2
Rabbit
Human, Mouse, Bat, Bovine, Pig (tested or 100% immunogen sequence identity)
Monkey, Rat, Dog (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (40 µg/ml), ELISA

Specificity and Use

PTGER2 / EP2 antibody was raised against synthetic 14 amino acid peptide from 3rd extracellular domain of human EP2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Bovine, Bat, Panda, Pig (100%); Marmoset, Rat, Dog, Elephant (93%); Turkey, Chicken, Platypus (86%).
LS-E28915 - Liquid - 50 µg - $145.00
Extracellular Domain
Human EP2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Immunohistochemistry: LS-A4202 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A4202 was determined to be 20-40 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About PTGER2 / EP2

P43116 NM_000956 NP_000947.2

PTGER2 Antibody, EP2 prostaglandin e2 receptor Antibody, EP2 prostaglandin receptor Antibody, EP2 Antibody, Pge2-r ep2 Antibody, PGE2 receptor EP2 subtype Antibody, Prostaglandin E receptor 2 Antibody, Prostanoid EP2 receptor Antibody, EP2 receptor Antibody, PGE receptor EP2 subtype Antibody

Prostaglandin E Receptor EP2 is a member of the Prostanoid Receptor subfamily. Along with several other receptor subtypes (EP1, EP3, and EP4), it mediates the diverse biological effects of Prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, induction of labor, cervical cancer, control of blood pressure, asthma, and more recently, Alzheimer's Disease.

Immunohistochemistry

Immunohistochemistry
Anti-EP2 antibody LS-A4202 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 9/25/2016

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