Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Specificity and Use
PROS1 / Protein S antibody was raised against native human PROS1.
Recognizes Protein S, a 77kD vitamin K-dependent glycoprotein. Protein S is produced by endothelium, the liver and megakaryocytes, but is found circulating in plasma. Protein S binds activated Protein C enabling inactivation of Factor Va and VIIIa, but it can also form a non-covalent complex with C4bp.
PROS1 Antibody, Protein S (alpha) Antibody, Protein S alpha Antibody, Protein Sa Antibody, PS22 Antibody, PS21 Antibody, Vitamin K-dependent protein S Antibody, THPH5 Antibody, THPH6 Antibody, PROS Antibody, PS24 Antibody, Protein S Antibody, PS23 Antibody, PS25 Antibody
PROS1 / Protein S is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.