Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone RCR-379] (IgG2a) to Human PROCR / EPCR
IHC - Frozen, Flow Cytometry, Functional Assay
Human PROCR / EPCR
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [RCR-379]
IHC - Frozen
Specificity and Use
PROCR / EPCR antibody was raised against tail base human EPCR-positive RE-1 cells
Human PROCR / EPCR
For immunohistology and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For inhibition of biological activity dilutions have to be made according to the amounts EPCR to be inhibited.
PROCR Antibody, Activated protein C receptor Antibody, CD201 Antibody, CD201 antigen Antibody, Centrocyclin Antibody, CCD41 Antibody, Endothelial protein C receptor Antibody, APC receptor Antibody, BA42O4.2 Antibody, CCCA Antibody, EPCR Antibody
PROCR / EPCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.