Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat, Human, Pig, Rabbit (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [U5]
IHC - Paraffin, IHC - Frozen, ICC (5 µg/ml), Western blot (1 µg/ml), Immunoprecipitation, Flow Cytometry
Specificity and Use
PRLR / Prolactin Receptor antibody was raised against purified rat liver prolactin receptor.
Recognizes the extracellular domain of human, rat, rabbit and pig prolactin receptor. Does not inhibit the interaction of prolactin with the receptor.
Suitable for use in Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot and Immunoprecipitation. Immunocytochemistry: 5 ug/ml. Immunohistochemistry: Frozen and paraffin sections. Western Blot: 1 ug/ml, detects bands of ~40 and ~100kD representing both the short and the long forms of the prolactin receptor.
lyophilized with 0.05% sodium azide
100 µl Reconstitute in 100 ul of Sterile PBS.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.