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Anti-PRKDC / DNA-PKcs Antibody LS-C9700

Ordering

Wt. Vol. Conc. Price
50 µg - - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Rabbit Polyclonal (IgG) to Human PRKDC / DNA-PKcs
Human, Rodent
IHC - Frozen, ICC
Unconjugated

Details

Human PRKDC / DNA-PKcs
Rabbit
Human, Rodent (tested or 100% immunogen sequence identity)
IgG Polyclonal
Affinity purified

Applications

IHC - Frozen (1:100 - 1:1000), ICC (1:100 - 1:1000)

Specificity and Use

PRKDC / DNA-PKcs antibody was raised against synthetic peptide from human PRKDC / DNA-PKcs.
Recognizes PRKDC. Species Reactivity: Human and rodent.
Suitable for use in Immunohistochemistry, Immunocytochemistry. Immunohistochemistry: Frozen sections. Not tested for paraffin. 1:100-1:1000. Immunocytochemistry: 1:100-1:1000.

Packaging

PBS, pH 7.2, 40% glycerol. No preservative added.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About PRKDC / DNA-PKcs

P78527 NM_006904 NP_008835.5

PRKDC Antibody, DNA-PK Antibody, DNAPK Antibody, DNPK1 Antibody, HYRC Antibody, HYRC1 Antibody, p350 Antibody, Scid Antibody, XRCC7 Antibody, DNA-PK catalytic subunit Antibody, DNA-PKcs Antibody, p460 Antibody, DNA-dependent protein kinase catalytic subunit Antibody

Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step.

Requested From: United States
Date Requested: 9/26/2016

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