Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse, Rat, Bat, Bovine, Horse, Pig, Rabbit
IHC - Paraffin, Western blot
Human, Mouse, Rat, Bat, Bovine, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Monkey, Dog, Guinea pig (at least 90% immunogen sequence identity)
IHC - Paraffin, Western blot (0.2 - 1 µg/ml)
Specificity and Use
PREB antibody was raised against synthetic peptide located between aa140-189 of human PREB (Q9HCU5, NP_037520). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Elephant, Bat, Rabbit, Horse, Pig (100%); Marmoset, Dog (91%); Guinea pig (90%); Opossum (84%); Mouse, Rat, Hamster, Bovine (83%).
Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription (By similarity). Guanine nucleotide exchange factor that activates SARA2. Required for the formation of COPII transport vesicles from the ER.