Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
PRDX3 Antibody, Antioxidant protein 1 Antibody, AOP1 Antibody, AOP-1 Antibody, HBC189 Antibody, Peroxiredoxin III Antibody, PRO1748 Antibody, Peroxiredoxin-3 Antibody, Prx-III Antibody, SP-22 Antibody, Peroxiredoxin 3 Antibody, Protein MER5 homolog Antibody
PRDX3 / Peroxiredoxin 3 is a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes.
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PRDX3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of PRDX3 (arrow) using rabbit polyclonal PRDX3 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRDX3 gene.
Western blot of PRDX3 Antibody in NCI-H460,MDA-MB231,HepG2 cell line lysates (35 ug/lane). PRDX3 (arrow) was detected using the purified antibody.(2 ug/ml)
Flow cytometric of MDA-MB468 cells using PRDX3 Antibody (bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.