Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Goat Polyclonal to Human PPY / Pancreatic Polypeptide
IHC - Paraffin, ELISA
Human PPY / Pancreatic Polypeptide
Human, Monkey (tested or 100% immunogen sequence identity)
Horse (at least 90% immunogen sequence identity)
IHC - Paraffin (5 µg/ml)
IHC - Paraffin
Specificity and Use
Synthetic peptide C-TRPRYGKRHKEDT from an internal region of human PPY (NP_002713.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%); Elephant, Horse (92%); Marmoset, Rat, Sheep, Bovine (85%).
LS-E25896 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B5911. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Distinctive expression and cellular distribution of dopamine receptors in the pancreatic islets of rats. Chen Y, Hong F, Chen H, Fan RF, Zhang XL, Zhang Y, Zhu JX. Cell and tissue research. 2014 Sep;357:597-606. [Full Text Article]
New perspectives of vesicular monoamine transporter 2 chemical characteristics in mammals and its constant expression in type 1 diabetes rat models. Hong F, Liu L, Fan RF, Chen Y, Chen H, Zheng RP, Zhang Y, Gao Y, Zhu JX. Translational research : the journal of laboratory and clinical medicine. 2014 Feb;163:171-82. [Full Text Article]
Differential expression and localization of neuropeptide Y peptide in pancreatic islet of diabetic and high fat fed rats. Ruipan Z, Xiangzhi M, Li L, Ying Z, Mingliang Q, Peng J, Jingwei L, Zijun Z, Yan G. Peptides. 2014 Apr;54:33-8. [Full Text Article]
PPY / Pancreatic Polypeptide belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake.