Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 4E6] (IgG1,k) to Human PPP2R1A
IHC, IHC - Paraffin, Western blot, ELISA
Human, Mouse, Rat, Bovine
IHC, Western blot
Human, Mouse, Rat, Bovine (tested or 100% immunogen sequence identity)
Specificity and Use
This peptide (NH2-Asp-Asp-Ser-Leu-Tyr-Pro-Ile-Ala-Val-Leu-Ile-Asp-Glu-COOH) corresponds to the N- terminal peptide of PP2A/A regulatory subunit having a MW of 65kD. The sequence used is amino acids 7-19.
PPP2R1A is a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.