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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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POU5F1 / OCT4 Antibody (N‑Terminus) LS‑C48532
Antibody
OCT4 antibody LS-C48532 is an unconjugated rabbit polyclonal antibody to OCT4 (POU5F1) from human, mouse, rat and other species. Validated for IHC, IP and WB.
Catalog
Size
Price
LS-C48532-30
30 µg
Unavailable
LS-C48532-100
100 µg (0.5 mg/ml)
Unavailable

Popular POU5F1 / OCT4 Products

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Lung: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Product Description

OCT4 antibody LS-C48532 is an unconjugated rabbit polyclonal antibody to OCT4 (POU5F1) from human, mouse, rat and other species. Validated for IHC, IP and WB.
About POU5F1 / OCT4
POU5F1 / OCT4 is a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. Q01860 NM_002701 NP_002692.2

POU5F1 Antibody, Oct-4 Antibody, OCT3 Antibody, OCT4 Antibody, OTF4 Antibody, POU class 5 homeobox 1 Antibody, Octamer-binding protein 3 Antibody, Octamer-binding protein 4 Antibody, OTF-3 Antibody, Oct-3 Antibody, OTF3 Antibody


Specifications

Target
Mouse POU5F1 / OCT4
Host
Rabbit
Reactivity
Mouse, Human, Rat, Bovine (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC (20 µg/ml)
  • Western blot (0.5 - 4 µg/ml)
  • Immunoprecipitation (20 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
POU5F1 / OCT4 antibody was raised against synthetic peptide mapping to the N-terminus of mouse Oct-4.
Epitope
N-Terminus
Specificity
The antibody reacts with 45 kD Oct-4 (also designated Oct-3A) and in a less extent 33 kD Oct-3B from human, mouse, and rat samples. Rat kidney tissue lysate can be used as a positive control.
Presentation
PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.01% Thimerosal.
Storage
Short term: -20°C; Long term: -70°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/25/2018

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