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Anti-POU5F1 / OCT4 Antibody (aa1-145) LS-C126083

Catalog Size Price
LS-C126083-100 100 µg Unavailable

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100% Guaranteed
Mouse Monoclonal (IgG1,k) to Human POU5F1 / OCT4
Human, Mouse
ICC, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human POU5F1 / OCT4
Mouse
Human, Mouse (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Protein G purified
Unmodified

Applications

  • ICC (1:100 - 1:200)
  • Western blot (1 - 2 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

POU5F1 / OCT4 antibody was raised against recombinant human Oct-4 protein, aa1-145.
aa1-145
Recognizes human Oct-4. Species cross-reactivity: mouse.
Suitable for use in Immunocytochemistry, Western Blot and Immunocytochemistry. Immunocytochemistry: 1:100-1:200. Western Blot: 1-2 ug/ml. Immunocytochemistry: 1:100-1:200.

Packaging

0.1 M Tris-glycine, pH 7.4, 150 mM sodium chloride, 0.05% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C.
For research use only.

About POU5F1 / OCT4

Q01860 NM_002701 NP_002692.2

POU5F1 Antibody, Oct-4 Antibody, OCT3 Antibody, OCT4 Antibody, OTF4 Antibody, POU class 5 homeobox 1 Antibody, Octamer-binding protein 3 Antibody, Octamer-binding protein 4 Antibody, OTF-3 Antibody, Oct-3 Antibody, OTF3 Antibody

POU5F1 / OCT4 is a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms.

Requested From: 
Date Requested: 12/14/2017

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