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Anti-POSTN / Periostin Antibody (aa24-811) LS-C150231

Ordering

Wt. Vol. Conc. Price
100 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular POSTN / Periostin Antibodies

Anti-POSTN / Periostin Antibody IHC-plus™ LS-B10443
Rabbit Polyclonal to Mouse POSTN / Periostin
Mouse, Human, Rat, Chicken
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Mouse POSTN / Periostin
Mouse
ICC, Western blot, Neutralization
Unconjugated

Details

Mouse POSTN / Periostin
Goat
Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • ICC (5 - 15 µg/ml)
  • Western blot (0.1 µg/ml)
  • Neutralization

Specificity and Use

POSTN / Periostin antibody was raised against s. frugiperda insect ovarian cell line Sf21-derived recombinant mouse Periostin/OSF-2 Asn24-Gln811 Accession # Q62009.
aa24-811
Detects Periostin/OSF-2 in direct ELISAs and Western blots.
Western Blot, 0.1 µg/ml, Recombinant Mouse Periostin/OSF-2. Immunocytochemistry, 5-15 µg/ml, Immersion fixed MC3T3-E1 mouse preosteoblast cell line. Neutralization, Measured by its ability to neutralize Periostin/OSF-2-mediated adhesion of the ATDC5 mouse chondrogenic cell. line. The Neutralization Dose (ND50) is typically 1-5 µg/ml in the presence of 5 µg/ml Recombinant Mouse Periostin/OSF-2.

Packaging

Lyophilized from 0.2 um filtered solution in PBS, trehalose
Sterile PBS. Resuspend to 500 ul
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About POSTN / Periostin

Q15063 NM_006475 NP_006466.2

POSTN Antibody, OSF2 Antibody, PDLPOSTN Antibody, Periostin isoform thy6 Antibody, Periostin isoform thy8 Antibody, RP11-412K4.1 Antibody, OSF-2 Antibody, Osteoblast-specific factor 2 Antibody, Periostin Antibody, Periostin isoform thy2 Antibody, Periostin isoform thy4 Antibody, PN Antibody

Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX By similarity. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.

Neutralization

Neutralization
Cell Adhesion Mediated by Periostin/OSF-2 and Neutralization by Mouse Periostin/ OSF-2 Antibody. Recombinant Mouse Periostin/OSF-2, immobilized onto a microplate, supports the adhesion of the ATDC5 mouse chondrogenic cell line in a dose-dependent manner (orange line). Adhesion elicited by Recombinant Mouse Periostin/OSF-2 (5 ug/m L) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse Periostin/ OSF-2 Isoform 2 Antigen Affinity-purified Polyclonal Antibody. The ND50 is typically 1-5 ug/ml.
 

Requested From: United States
Date Requested: 12/2/2016

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