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Participates in O-mannosyl glycosylation. May be responsible for the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins. Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Gene Name: | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
Synonyms: | POMGNT1, GNTI.2, GnT I.2, GnT-I.2, LGMD2O, MEB, MDDGB3, MGAT1.2, MDDGA3, MDDGC3 |
Target Sequences: | NM_017739 NP_060209.3 Q8WZA1 |
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