Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, IHC - Frozen, ICC, Western blot, Radioimmunoassay
Mouse Polysialic Acid
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
IHC - Paraffin
IHC - Frozen (1:200 - 1:400)
ICC (1:200 - 1:400)
Western blot (1:500 - 1:1000)
Specificity and Use
Polysialic Acid antibody was raised against viable Meningococcus group B (strain 355).
Recognizes mouse Polysialic Acid NCAM at 150-300kD. Reacts with alpha 2-8 linked neuraminic acid (NeuAc-alpha 2-8) n with n >10. Works well on all species expressing PSA-NCAM. Species Crossreactivity: Human, rat, most common vertebrates.
Suitable for use in Western Blot, Immunocytochemistry, Immunohistochemistry and RIA. Western Blot: 1:500-1:1000. Immunocytochemistry: 1:200-1:400; Works on live and fixed cells. Immunohistochemistry: 1:200-1:400; Works on tissue sections either frozen or fixed with any kind of fixative. Immunohistochemistry (Paraffin): Requires retrieval with EDTA, pH 8.0.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.