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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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POLM / DNA Polymerase Mu Antibody (aa6‑18) IHC‑plus™ LS‑B406 Best Seller
Note: This antibody replaces LS-C19033, LS-C64805
DNA Polymerase Mu antibody LS-B406 is an unconjugated rabbit polyclonal antibody to human DNA Polymerase Mu (POLM). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B406-50
50 µg (1 mg/ml)
Unavailable

Popular POLM / DNA Polymerase Mu Products

POLM antibody LS-C102575 Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Horse, Pig, Rabbit
Applications: Western blot
Western blot of DNA Polymerase Mu antibody
Species: Human
Applications: Western blot, ELISA
Western blot analysis of DNA Polymerase mu expression in K562 (A); Jurkat (B) whole cell lysates.
Species: Human
Applications: Western blot
POLM antibody LS-C102575 Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Chimpanzee, Mouse, Rat, Horse, Pig, Rabbit
Applications: Western blot

Product Description

DNA Polymerase Mu antibody LS-B406 is an unconjugated rabbit polyclonal antibody to human DNA Polymerase Mu (POLM). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
About POLM / DNA Polymerase Mu
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. Q9NP87 NM_013284 NP_037416.1

POLM Antibody, Polmu Antibody, Polymerase (DNA directed), mu Antibody, Pol iota Antibody, Pol Mu Antibody, Tdt-N Antibody, DNA polymerase mu Antibody, Polymerase (DNA-directed), mu Antibody, Terminal transferase Antibody


Specifications

Target
Human POLM / DNA Polymerase Mu
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide from human POLM.
Epitope
aa6-18
Specificity
Aa 6-18 of Human POLM m (DNA polymerase mu). POLM m is a template-directed terminal deoxynucleotide transferase that shows a preferential expression in proliferating lymphoid cells.
Usage
Immunohistochemistry: LS-B406 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B406 was determined to be 5 ug/ml.
Presentation
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B406 concentration 5 ug/ml.
Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B406 concentration 5 ug/ml.

Immunohistochemistry

Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B406 concentration 5 ug/ml.
Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B406 concentration 5 ug/ml.

Immunohistochemistry

Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B406 concentration 5 ug/ml.
Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B406 concentration 5 ug/ml.

Immunohistochemistry

Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B406 concentration 5 ug/ml.
Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B406 concentration 5 ug/ml.


Requested From: 
Date Requested: 6/24/2018

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