LSBio The Immunohistochemistry Antibody Company
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All ELISA Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-PMS2 Antibody (aa58-81, clone 349.29.5.2) LS-C59521


Wt. Vol. Conc. Price
100 µg - 1 mg/ml Unavailable

Related Products

23 PMS2 Antibodies

Most Popular PMS2 Antibodies

Anti-PMS2 Antibody (aa623-639, clone 163C1251) IHC-plus™ LS-B1980
Mouse Monoclonal [clone 163C1251] (IgG1) to Human PMS2
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-PMS2 Antibody (aa58-81, clone 349.29.5.2) LS-C59521
Mouse Monoclonal [clone 349.29.5.2] to Human PMS2
Human, Mouse, Rat, Hamster
Western blot, ELISA
Western blot Image
Anti-PMS2 Antibody (aa125-174) IHC-plus™ LS-B5688
Rabbit Polyclonal (IgG) to Human PMS2
IHC - Paraffin, ELISA
Immunohistochemistry Image
Anti-PMS2 Antibody (clone 2G5) LS-C338149
Mouse Monoclonal [clone 2G5] (IgG2b) to Human PMS2
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-PMS2 Antibody LS-C346151
Rabbit Polyclonal (IgG) to Human PMS2
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot, Immunoprecipitation
Immunofluorescence Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 349.29.5.2] to Human PMS2
Human, Mouse, Rat, Hamster
Western blot, ELISA


Human PMS2
Human, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Monoclonal [349.29.5.2]
Protein A purified


  • Western blot (1:500 - 1:2000)
  • ELISA (1:5000 - 1:20000)

Specificity and Use

PMS2 antibody was raised against recombinant human PMS2 corresponding to the first 133 amino acid residues of the protein. The clone was produced using conventional hybridoma technology.
PMS2-134 and reacts with full length version of PMS2 in human and hamster tissues. The epitope was putatively mapped to amino acids 58-81 of human PMS2. BLAST analysis indicates that this sequence is 100% identical for human, mouse, rat and chimpanzee. No specific information is available for reactivity with PMS2 protein from other sources
This antibody has been tested for use in ELISA, western blotting and immunoprecipitation. Specific conditions for western blotting reactivity should be optimized by the end user. Expect a band approximately 96 kD in size corresponding to human PMS2 by western blotting in most cell lines and tissues as PMS2 is ubiquitously expressed.


0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2 Clone: 349.29.5.2, 0.1% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About PMS2

P54278 NM_000535 NP_000526.1

PMS2 Antibody, HNPCC4 Antibody, H_DJ0042M02.9 Antibody, PMS2CL Antibody, PMSL2 Antibody, PMS1 protein homolog 2 Antibody

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MLH1 to form MutL alpha. DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2.

Western blot

Western blot
Anti-PMS2 Antibody - Western Blot. Western blot analysis is shown using Protein A Purified Mouse Monoclonal Anti-PMS2 antibody to detect human PMS2 protein present in H157 cell lysates. Approximately 5,10 and 30 ug of cell lysate was loaded on a 4-12% NuPage SDS-PAGE gel using MES buffer. The blot was incubated with a 1:1000 dilution of the antibody at room temperature followed by washing. A 1:20000 dilution of HRP conjugated Gt-anti-Mouse IgG preceded color development using Pierce Chemicals SuperSignal substrate. Comparison to a molecular weight marker (not shown) indicates a single band of ~96.0 kD corresponding to the expected molecular weight for human PMS2 protein. Other detection systems will yield similar results. Personal communication Morphotek Inc.

Requested From: 
Date Requested: 4/25/2017

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2017 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number