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Anti-PMS2 Antibody (aa58-81, clone 349.29.5.2) LS-C59521


Wt. Vol. Conc. Price
100 µg - - $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular PMS2 Antibodies

Anti-PMS2 Antibody (aa623-639, clone 163C1251) IHC-plus™ LS-B1980
Mouse Monoclonal [clone 163C1251] (IgG1) to Human PMS2
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-PMS2 Antibody (aa125-174) IHC-plus™ LS-B5688
Rabbit Polyclonal (IgG) to Human PMS2
IHC - Paraffin, ELISA
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100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 349.29.5.2] to Human PMS2
Human, Mouse, Rat, Hamster
Western blot, Immunoprecipitation, ELISA


Human PMS2
Human, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Monoclonal [349.29.5.2]
Protein A purified


  • Western blot (1:500 - 1:2000)
  • Immunoprecipitation
  • ELISA (1:5000 - 1:20000)

Specificity and Use

PMS2 antibody was raised against recombinant human PMS2 corresponding to the first 133 amino acid residues of the protein. The clone was produced using conventional hybridoma technology.
PMS2-134 and reacts with full length version of PMS2 in human and hamster tissues. The epitope was putatively mapped to amino acids 58-81 of human PMS2. BLAST analysis indicates that this sequence is 100% identical for human, mouse, rat and chimpanzee. No specific information is available for reactivity with PMS2 protein from other sources
This antibody has been tested for use in ELISA, western blotting and immunoprecipitation. Specific conditions for western blotting reactivity should be optimized by the end user. Expect a band approximately 96 kD in size corresponding to human PMS2 by western blotting in most cell lines and tissues as PMS2 is ubiquitously expressed.


0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2 Clone: 349.29.5.2, 0.1% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About PMS2

P54278 NM_000535 NP_000526.1

PMS2 Antibody, HNPCC4 Antibody, H_DJ0042M02.9 Antibody, PMS2CL Antibody, PMSL2 Antibody, PMS1 protein homolog 2 Antibody

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MLH1 to form MutL alpha. DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2.

Western blot

Western blot
Anti-PMS2 Antibody - Western Blot. Western blot analysis is shown using Protein A Purified Mouse Monoclonal Anti-PMS2 antibody to detect human PMS2 protein present in H157 cell lysates. Approximately 5,10 and 30 ug of cell lysate was loaded on a 4-12% NuPage SDS-PAGE gel using MES buffer. The blot was incubated with a 1:1000 dilution of the antibody at room temperature followed by washing. A 1:20000 dilution of HRP conjugated Gt-anti-Mouse IgG preceded color development using Pierce Chemicals SuperSignal substrate. Comparison to a molecular weight marker (not shown) indicates a single band of ~96.0 kD corresponding to the expected molecular weight for human PMS2 protein. Other detection systems will yield similar results. Personal communication Morphotek Inc.

Requested From: United States
Date Requested: 10/22/2016

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