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Anti-PML Antibody (aa1-581) LS-C9654

Catalog Size Price
LS-C9654-200 200 µg (1 mg/ml) Unavailable

Related Products

62 PML Antibodies

Most Popular PML Antibodies

Anti-PML Antibody (aa470-499) LS-C98465
Rabbit Polyclonal to Human PML
Human
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Anti-PML Antibody (aa588-637) IHC-plus™ LS-B3501
Rabbit Polyclonal (IgG) to Human PML
Human, Mouse, Rat, Bovine, Guinea pig, Horse
IHC, IHC - Paraffin, Western blot
Unconjugated
Anti-PML antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3501 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-PML Antibody (clone 36-1-104) LS-C179721
Mouse Monoclonal [clone 36-1-104] (IgG2b)
Mouse
ICC, Western blot
Unconjugated
Immunocytochemistry Image
Anti-PML Antibody (aa59-239) LS-C296061
Rabbit Polyclonal (IgG) to Human PML
Human
IHC, Western blot
Unconjugated
Western blot of recombinant PML.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-PML Antibody (aa59-239, Cy3) LS-C702195
Rabbit Polyclonal (IgG) to Human PML
Human
IHC, Western blot
Cy3 Conjugated
Western blot of recombinant PML.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

100% Guaranteed
Mouse Monoclonal (IgG2b) to Mouse PML
Mouse
ICC, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Mouse PML
Mouse
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Protein G purified
Unmodified

Applications

  • ICC
  • Western blot (0.5 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

PML antibody was raised against 6His fusion protein corresponding to aa1-581 of mouse PML (promyelocytic leukemia protein).
aa1-581
Recognizes mouse PML, Mr ~90-106kD, depending on degree of protein modification. Does not cross-react with human. MEF1 cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with This antibody. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system.
Suitable for use in Western Blot and Immunocytochemistry. Western Blot: 0.5-1 ug/ml of this lot detected PML in RIPA lysates from mouse embryo fibroblast (MEF1) cells. Immunocytochemistry: An independent laboratory showed positive immunostaining for PML in MEF1 cells fixed with 4% paraformaldehyde and permeabilized with 0.2% Triton X-100.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About PML

P29590 NM_002675 NP_002666.1

PML Antibody, PP8675 Antibody, Promyelocytic leukemia Antibody, Protein PML Antibody, TRIM19 Antibody, Promyelocytic leukemia protein Antibody, RING finger protein 71 Antibody, MYL Antibody, RNF71 Antibody

Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMO-mediated modifications and interactions.

Requested From: 
Date Requested: 5/22/2018

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