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Anti-PLN / Phospholamban Antibody (phospho-Ser16) LS-C38229

Note: This antibody replaces LS-C86189

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $635
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PLN / Phospholamban Antibodies

Anti-PLN / Phospholamban Antibody (aa2-25) IHC-plus™ LS-B2358
Mouse Monoclonal (IgG2a) to Dog PLN / Phospholamban
Dog, Human, Bovine, Pig
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-PLN / Phospholamban Antibody (aa3-14) IHC-plus™ LS-B8337
Goat Polyclonal to Human PLN / Phospholamban
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-PLN / Phospholamban Antibody (phospho-Thr17, Biotin) LS-C266487
Rabbit Polyclonal (IgG) to Human PLN / Phospholamban
Human
ELISA, Dot Blot
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human PLN / Phospholamban
Human, Bovine
Western blot, ELISA
Unconjugated

Details

Human PLN / Phospholamban
Rabbit
Human, Bovine (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.5 - 2 µg/ml)
  • ELISA

Specificity and Use

PLN / Phospholamban antibody was raised against synthetic peptide corresponding to aa14-25 of human cardiac phospholamban with a cysteine added at the C-terminal (RA[pS]TIEMPQQAR-C) (KLH).
pSer16
Recognizes human Phospholamban phosphorylated (Ser16) (Mr 5-25kD). Species cross-reactivity: bovine. Species sequence Homology: mouse, rat, rabbit, porcine and canine.
Suitable for use in ELISA and Western Blot. Proteins were visualized using a goat anti-rabbit IgG labeled with HRP and a chemiluminescence detection system. Note: Do not boil cardiac preparation. Boiling may reduce the 25kD pentamer in to tri-, di- or monomers. In addition, phosphorylation may disrupt the pentamer into dimers and monomers. Additional non-specific bands may be detected in some lysates (Mr 75 & 100kD).

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About PLN / Phospholamban

P26678 NM_002667 NP_002658.1

PLN Antibody, CMD1P Antibody, CMH18 Antibody, PLB Antibody, Cardiac phospholamban Antibody, Phospholamban Antibody

Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.

Requested From: United States
Date Requested: 12/9/2016

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