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Anti-PLK1 / PLK-1 Antibody IHC-plus™ LS-B4225

Note: This antibody replaces LS-C109374

Ordering

Wt. Vol. Conc. Price
- 50 µl 1 mg/ml Unavailable

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100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human PLK1 / PLK-1
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human PLK1 / PLK-1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot (1:500 - 1:3000)

Specificity and Use

PLK1 / PLK-1 antibody was raised against recombinant protein fragment containing a sequence corresponding to a region within amino acids 161 and 440 of Human PLK1.
Human PLK1. Predicted cross-reactivity based on amino acid sequence homology: mouse (95%), rat (95%), bovine (95%).

Packaging

0.1 M Tris-glycine, pH 7, 10% Glycerol, 0.01% Thimerosal
Aliquot and store at -20°C. Minimize freezing and thawing.
For research use only.

Publications (1)

1
Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide. Triscott J, Lee C, Hu K, Fotovati A, Berns R, Pambid M, Luk M, Kast RE, Kong E, Toyota E, Yip S, Toyota B, Dunn SE. Oncotarget. Oct;3:1112-23. [Full Text Article] [PubMed:23047041] [PMC:PMC3717961]

About PLK1 / PLK-1

P53350 NM_005030 NP_005021.2

PLK1 Antibody, Polo like kinase Antibody, Polo-like kinase (Drosophila) Antibody, Polo-like kinase 1 Antibody, STPK13 Antibody, Polo (Drosophia)-like kinase Antibody, PLK Antibody, PLK-1 Antibody

Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis.

Immunohistochemistry

Immunohistochemistry
Anti-PLK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4225 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-PLK1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4225 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-PLK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4225 concentration 10 ug/ml.

Western blot

Western blot
Sample(30 ug whole cell lysate). A: Raji. 7.5% SDS PAGE. PLK1 antibody diluted at 1:1000.

Requested From: 
Date Requested: 4/27/2017

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