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Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.
Gene Name: | perilipin 1 |
Synonyms: | PLIN1, FPLD4, PERI, Perilipin-1, PLIN, Perilipin, Perilipin 1 |
Target Sequences: | NM_002666 NP_002657.3 O60240 |
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