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Anti-PLG / Plasmin / Plasminogen Antibody (clone 4D2) LS-C58310

Ordering

Wt. Vol. Conc. Price
200 µg - - $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PLG / Plasmin / Plasminogen Antibodies

Anti-PLG / Plasmin / Plasminogen Antibody LS-C150840
Rabbit Polyclonal (IgG)
Rat
IHC - Frozen, Western blot, ELISA
Unconjugated
Anti-PLG / Plasmin / Plasminogen Antibody (clone 10A1) IHC-plus™ LS-B7839
Mouse Monoclonal [clone 10A1] (IgG1,k) to Human PLG / Plasmin / Plasminogen
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-PLG / Plasmin / Plasminogen Antibody IHC-plus™ LS-B10241
Sheep Polyclonal to Mouse PLG / Plasmin / Plasminogen
Mouse, Human, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 4D2] (IgG2b) to Human PLG / Plasmin / Plasminogen
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human PLG / Plasmin / Plasminogen
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [4D2]
Unconjugated
Ion exchange chromatography
Unmodified

Applications

  • IHC - Paraffin
  • ELISA

Specificity and Use

PLG / Plasmin / Plasminogen antibody was raised against purified human plasminogen.
Recognizes human plasminogen, a single chain beta globulin of 80-90kD. It is a circulating zymogen that is converted to the active enzyme plasmin (fibrinolysin) by plasminogen activators. The main function of plasmin is to dissolve fibrin and thus break up blood clots. Plasmin also plays a proteolytic role in processes such as embryonic development, tissue remodeling, tumor invasion and inflammation. Plasminogen deficiency may be a cause of thrombosis, or may be acquired through acute liver disease, acute disseminated intravascular coagulation or through thrombolytic therapy with plasminogen activators. Does not cross-react with other human serum proteins.
Immunohistology: This product does not require protein digestion pre-treatment of paraffin embedded sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin embedded sections.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About PLG / Plasmin / Plasminogen

P00747 NM_000301 NP_000292.1

PLG Antibody, Plasmin Antibody, Plasminogen Antibody

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis.

Requested From: United States
Date Requested: 12/3/2016

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