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Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.
Gene Name: | pleckstrin homology domain containing, family G (with RhoGef domain) member 5 |
Synonyms: | PLEKHG5, DSMA4, NFKB activating protein, KIAA0720, GEF720, Syx, Tech |
Target Sequences: | AK024676 |
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