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Anti-PLCG1 Antibody (phospho-Tyr783) LS-C9603

Ordering
Wt. Vol. Conc. Price
200 µg - - $515
Inquire for larger quantities

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59 PLCG1 Antibodies
11 PLCG1 Elisa Kits
1 PLCG1 Protein

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Rabbit Polyclonal (IgG) to Human PLCG1
Human, Mouse, Rat, Bovine, Rabbit
Western blot
Unconjugated

Details

Human PLCG1
Rabbit
Human, Mouse, Rat, Bovine, Rabbit (tested or 100% immunogen sequence identity)
IgG Polyclonal
Protein A purified

Applications

Western blot

Specificity and Use

PLCG1 antibody was raised against kLH-conjugated, synthetic peptide corresponding to aa surrounding phospho-Tyr783 of human PLCg-1.
pTyr783
Recognizes PLCg-1 phosphorylated on Tyr783, Mr ~135kD. Species cross-reactivity: Human and mouse. Cross-reactivity with rat, rabbit and bovine expected due to sequence homology.
Suitable for use in Western Blot. Western Blot Analysis: 1-2 ug/ml of this lot detected phospho-PLCg-1 in RIPA lysates from EGF-stimulated A431 cells.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About PLCG1

P19174 NM_002660 NP_002651.2

PLCG1 Antibody, Phospholipase C, gamma 1 Antibody, Phospholipase C-148 Antibody, Phosphoinositidase C Antibody, Phospholipase C-II Antibody, Inositoltrisphosphohydrolase Antibody, PLC-gamma-1 Antibody, PLC1 Antibody, PLC-148 Antibody, PLC-II Antibody, PLC148 Antibody, NCKAP3 Antibody, Phospholipase C-gamma-1 Antibody, PLCgamma1 Antibody

PLCG1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras.
(More About PLCG1)
Requested From: United States
Date Requested: 9/24/2016
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