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PLCG1 antibody LS-C9603 is an unconjugated rabbit polyclonal antibody to PLCG1 from human, mouse, rat and other species. Validated for WB.
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Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat, Bovine
Applications:
IHC, IHC - Paraffin, Western blot
Product Description
PLCG1 antibody LS-C9603 is an unconjugated rabbit polyclonal antibody to PLCG1 from human, mouse, rat and other species. Validated for WB.
About PLCG1
PLCG1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras.
P19174
NM_002660
NP_002651.2
PLCG1 Antibody, Phospholipase C, gamma 1 Antibody, Phospholipase C-148 Antibody, Phosphoinositidase C Antibody, Phospholipase C-II Antibody, Inositoltrisphosphohydrolase Antibody, PLC-gamma-1 Antibody, PLC1 Antibody, PLC-148 Antibody, PLC-II Antibody, PLC148 Antibody, NCKAP3 Antibody, Phospholipase C-gamma-1 Antibody, PLCgamma1 Antibody
Specifications
Target
Human PLCG1
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein A purified
Modifications
Unmodified
Applications
- Western blot
- (applications tested for the base form of this product only)
Immunogen
PLCG1 antibody was raised against kLH-conjugated, synthetic peptide corresponding to aa surrounding phospho-Tyr783 of human PLCg-1.
Epitope
pTyr783
Specificity
Recognizes PLCg-1 phosphorylated on Tyr783, Mr ~135kD. Species cross-reactivity: Human and mouse. Cross-reactivity with rat, rabbit and bovine expected due to sequence homology.
Usage
Suitable for use in Western Blot. Western Blot Analysis: 1-2 ug/ml of this lot detected phospho-PLCg-1 in RIPA lysates from EGF-stimulated A431 cells.
Presentation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
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