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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PKP2 / Plakophilin 2 Antibody (aa838‑866) LS‑C163752
Plakophilin 2 antibody LS-C163752 is an unconjugated rabbit polyclonal antibody to human Plakophilin 2 (PKP2). Validated for IHC and WB.
Catalog
Size
Price
LS-C163752-400
400 µl
Unavailable

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Product Description

Plakophilin 2 antibody LS-C163752 is an unconjugated rabbit polyclonal antibody to human Plakophilin 2 (PKP2). Validated for IHC and WB.
About PKP2 / Plakophilin 2
PKP2 / Plakophilin 2 is a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. Q99959 NM_004572 NP_004563.2

PKP2 Antibody, ARVD9 Antibody, Plakophilin 2 Antibody, Plakophilin-2 Antibody


Specifications

Target
Human PKP2 / Plakophilin 2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E2056 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C163752. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa838-866
Specificity
This PKP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 838-866 amino acids from the C-terminal region of human PKP2.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

PKP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
PKP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

PKP2 Antibody western blot of K562 cell line lysates (35 ug/lane). The PKP2 antibody detected the PKP2 protein (arrow).
PKP2 Antibody western blot of K562 cell line lysates (35 ug/lane). The PKP2 antibody detected the PKP2 protein (arrow).

Immunohistochemistry

PKP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
PKP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

PKP2 Antibody western blot of K562 cell line lysates (35 ug/lane). The PKP2 antibody detected the PKP2 protein (arrow).
PKP2 Antibody western blot of K562 cell line lysates (35 ug/lane). The PKP2 antibody detected the PKP2 protein (arrow).

Immunohistochemistry

PKP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
PKP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

PKP2 Antibody western blot of K562 cell line lysates (35 ug/lane). The PKP2 antibody detected the PKP2 protein (arrow).
PKP2 Antibody western blot of K562 cell line lysates (35 ug/lane). The PKP2 antibody detected the PKP2 protein (arrow).

Immunohistochemistry

PKP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
PKP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

PKP2 Antibody western blot of K562 cell line lysates (35 ug/lane). The PKP2 antibody detected the PKP2 protein (arrow).
PKP2 Antibody western blot of K562 cell line lysates (35 ug/lane). The PKP2 antibody detected the PKP2 protein (arrow).


Requested From: 
Date Requested: 6/18/2018

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