Human PKM / Pyruvate Kinase, Muscle

Rabbit

Human, Mouse, Rat (tested or 100% immunogen sequence identity)

Polyclonal

Unconjugated

Protein G purified

Unmodified

KLH-conjugated synthetic peptide from the C-Terminus of human PKM2.

PKM2 is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP for generating ATP. There are 4 isoenzymes of pyruvate kinase in mammals (L, R, M1 and M2) encoded by 2 different genes: PKLR and PKM. The L and R isoenzymes are generated from the PKLR by differential splicing of RNA; the M1 and M2 forms are produced from the PKM gene by differential splicing. L type is the major isozyme in liver, R is found in red cells, M1 is the main form in muscle, heart and brain, and M2 is found in early fetal tissues as well as in most cancer cells. This antibody binds to both M1 and M2 isoforms of PKM.

• Western blot (1:100 - 1:500)
• ELISA (1:500 - 1:1000)

This antibody binds to both M1 and M2 isoforms of PKM.

PBS, pH 7.4, 0.09% sodium azide, 12.5% glycerol.

Store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P14618 NCBI: NM_002654 NP_002645.3