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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PKM / Pyruvate Kinase, Muscle Antibody (aa350‑450, DY488) LS‑C143417
Pyruvate Kinase, Muscle antibody LS-C143417 is a DY488-conjugated rabbit polyclonal antibody to human Pyruvate Kinase, Muscle (PKM). Validated for ICC, IF, IHC and WB.
Catalog
Size
Price
LS-C143417-100
100 µl
Unavailable

Popular PKM / Pyruvate Kinase, Muscle Products

Anti-PKM antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1450 concentration 5 ug/ml.
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Anti-PKM2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2445 dilution 1:100.
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PKM2 / Pyruvate Kinase antibody LS-C117151 Western blot of Fetal Heart lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Product Description

Pyruvate Kinase, Muscle antibody LS-C143417 is a DY488-conjugated rabbit polyclonal antibody to human Pyruvate Kinase, Muscle (PKM). Validated for ICC, IF, IHC and WB.
About PKM / Pyruvate Kinase, Muscle
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. P14618 NM_002654 NP_002645.3

PKM Antibody, p58 Antibody, PK3 Antibody, PKM2 Antibody, Pyruvate Kinase Antibody, Pyruvate kinase 2/3 Antibody, Pyruvate kinase, m1 Antibody, Pyruvate kinase, muscle Antibody, TCB Antibody, Tumor M2-PK Antibody, OIP-3 Antibody, OIP3 Antibody, Opa-interacting protein 3 Antibody, CTHBP Antibody, PK, muscle type Antibody, PK2 Antibody, Pyruvate kinase isozymes M1/M2 Antibody, Pyruvate kinase muscle isozyme Antibody, THBP1 Antibody


Specifications

Target
Human PKM / Pyruvate Kinase, Muscle
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
DyLight 488. Also available Unconjugated or conjugated with Biotin, DY650, DY550.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • ICC (1:200)
  • Immunofluorescence
  • Western blot (0.5 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
A synthetic peptide made to the internal region of human PKM2 protein (within residues 350-450). [Swiss-Prot# P14618]. Percent identity by BLAST analysis: Bovine (95%).
Epitope
aa350-450
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

PKM2 Antibody - IHC of PKM2 in liver tissue.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PKM2 Antibody - IHC of PKM2 in liver tissue. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry/Immunofluorescence: PKM2 Antibody - Immunocytochemical analysis of PKM2 in HeLa cells.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry/Immunofluorescence: PKM2 Antibody - Immunocytochemical analysis of PKM2 in HeLa cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

PKM2 Antibody - Western blot of PKM2 in MCF7 whole cell lysates.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PKM2 Antibody - Western blot of PKM2 in MCF7 whole cell lysates. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

PKM2 Antibody - IHC of PKM2 in liver tissue.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PKM2 Antibody - IHC of PKM2 in liver tissue. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry/Immunofluorescence: PKM2 Antibody - Immunocytochemical analysis of PKM2 in HeLa cells.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry/Immunofluorescence: PKM2 Antibody - Immunocytochemical analysis of PKM2 in HeLa cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

PKM2 Antibody - Western blot of PKM2 in MCF7 whole cell lysates.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PKM2 Antibody - Western blot of PKM2 in MCF7 whole cell lysates. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

PKM2 Antibody - IHC of PKM2 in liver tissue.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PKM2 Antibody - IHC of PKM2 in liver tissue. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry/Immunofluorescence: PKM2 Antibody - Immunocytochemical analysis of PKM2 in HeLa cells.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry/Immunofluorescence: PKM2 Antibody - Immunocytochemical analysis of PKM2 in HeLa cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

PKM2 Antibody - Western blot of PKM2 in MCF7 whole cell lysates.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PKM2 Antibody - Western blot of PKM2 in MCF7 whole cell lysates. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

PKM2 Antibody - IHC of PKM2 in liver tissue.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PKM2 Antibody - IHC of PKM2 in liver tissue. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry/Immunofluorescence: PKM2 Antibody - Immunocytochemical analysis of PKM2 in HeLa cells.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunocytochemistry/Immunofluorescence: PKM2 Antibody - Immunocytochemical analysis of PKM2 in HeLa cells. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

PKM2 Antibody - Western blot of PKM2 in MCF7 whole cell lysates.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PKM2 Antibody - Western blot of PKM2 in MCF7 whole cell lysates. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/17/2018

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