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PKD1 / Polycystin

polycystic kidney disease 1 (autosomal dominant)

PKD1 / Polycystin is a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene. Also, six pseudogenes, closely linked in a known duplicated region on chromosome 16p, have been described.

Gene Name: polycystic kidney disease 1 (autosomal dominant)
Synonyms: PKD1, PBP, Polycystin, TRPP1, Pc-1, Polycystin 1, Polycystin-1
Target Sequences: NM_000296 NP_000287.3 P98161

☰ Filters
Antibodies (12)
ELISA Kits (6)
Proteins (1)
Custom (1)
Primary (12)
Recombinant (1)
Sandwich (5)
PKD1 / Polycystin (19)
Human (14)
Mouse (6)
Rat (3)
Dog (1)
Monkey (1)
Pig (1)
IHC (5)
IHC-P (4)
WB (3)
ELISA (6)
IF (2)
IP (1)
Peptide-ELISA (3)
rabbit (9)
goat (2)
rabbit-new zealand white (1)
Product Group
IHCPlus (2)
IgG (8)
polyclonal pc (12)
96-Well Strip Plate (6)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (9)
aa3725-3735 (2)
aa2281-2292 (1)
aa3044-3066 (1)
aa4289-4300 (1)
No (19)
Plasma (5)
Serum (5)
Tissue Homogenates (1)
GST, N-terminus (1)
Human (1)
Wheat Germ Extract (1)
PKD1 / Polycystin Antibody - Anti-PKD1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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PKD1 / Polycystin Goat anti-Human Polyclonal (aa4289-4300) Antibody
Human
IF, IHC, IHC-P, IP, Peptide-ELISA
Unconjugated
50 µg/$460
PKD1 / Polycystin Antibody - Immunohistochemistry Dilution at 1:600 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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PKD1 / Polycystin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
PKD1 / Polycystin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PKD1 / Polycystin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PKD1 / Polycystin Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PKD1 / Polycystin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Select
PKD1 / Polycystin Rabbit anti-Human Polyclonal (aa3044-3066) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
PKD1 / Polycystin Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
PKD1 / Polycystin Goat anti-Human Polyclonal (aa2281-2292) Antibody
Mouse, Dog, Rat, Pig, Human
Peptide-ELISA
Unconjugated
100 µg/$467
PKD1 / Polycystin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PKD1 / Polycystin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
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PKD1 / Polycystin Rabbit anti-Human Polyclonal (aa3725-3735) Antibody
Mouse, Human
ELISA, IHC, IHC-P
Unconjugated
60 µl/$460
Select
PKD1 / Polycystin Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$393
PKD1 / Polycystin Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using PKD1 Polyclonal Antibody at dilution of 1:40.
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PKD1 / Polycystin Rabbit anti-Human Polyclonal (aa3725-3735) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
PKD1 / Polycystin Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µg/$357
PKD1 / Polycystin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
Select
Wheat Germ Extract
GST, N-terminus
36.74 kDa
10 µg/$479; 25 µg/$670
PKD1 / Polycystin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
PKD1 / Polycystin ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
PKD1 / Polycystin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PKD1 / Polycystin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Viewing 1-19 of 19 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).