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Anti-PITX3 Antibody (N-Terminus) IHC-plus™ LS-B2606

Note: This antibody replaces LS-C17510


Wt. Vol. Conc. Price
25 µg - 0.25 mg/ml $395

LSBio (Direct) LSBio (Direct)

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Rabbit Polyclonal (IgG) to Mouse PITX3
Mouse, Human
IHC - Paraffin, Immunofluorescence, Western blot


Mouse PITX3
Mouse, Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


IHC - Paraffin (5 µg/ml), Immunofluorescence (0.7 - 2 µg/ml), Western blot (1 - 3 µg/ml)

Specificity and Use

PITX3 antibody was raised against synthetic peptide derived from the N-terminal region of the mouse PiTX3 protein.
Recognizes mouse PiTX3 protein. Reactivity has been confirmed with fetal mouse brain homogenate.
Immunohistochemistry: LS-B2606 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2606 was determined to be 5 ug/ml. Western Blot: 1-3 ug/ml. Identifies a single band at ~32kD. Bands of unknown origin are observed at ~40 and 50kD.


PBS, pH 7.4, 0.1% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About PITX3

O75364 NM_005029 NP_005020.1

PITX3 Antibody, CTPP4 Antibody, Homeobox protein PITX3 Antibody, Paired-like homeodomain 3 Antibody, Pituitary homeobox 3 Antibody

Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons. Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.


Anti-PITX3 antibody IHC of human brain, cortex, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2606 concentration 5 ug/ml.

Requested From: United States
Date Requested: 12/1/2015

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