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Anti-PINK1 Antibody (N-Terminus, Biotin) LS-C141175

Catalog Size Price
LS-C141175-100 100 µl Unavailable

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Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

100% Guaranteed
Rabbit Polyclonal to Human PINK1
Human, Mouse, Rat
Western blot (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human PINK1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Biotin. Also available Unconjugated or conjugated with DY650, DY488, DY550.
Affinity purified
Unmodified

Applications

  • Western blot (1:500)
  • (applications tested for the base form of this product only)

Specificity and Use

PINK1 antibody was raised against an N-terminal region synthetic peptide made to the human Pink1 protein sequence (between residues 1-50)
N-Terminus
Pink1.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.05% sodium azide
Store at 4°C. Do not freeze.
For research use only.

About PINK1

Q9BXM7 NM_032409 NP_115785.1

PINK1 Antibody, BRPK Antibody, PTEN induced putative kinase 1 Antibody, PARK6 Antibody, PTEN-induced putative kinase Antibody, Protein kinase BRPK Antibody

Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.

Western blot

Western Blot detection of murine PINK1 using LS-C2845. 1: molecular weight marker. 2: MES cell Mitochondria (20 ug). 3: MES cytosol (20 ug). 4: MES nuclear (20 ug) as negative control. 5: Purified human cytochrome C (0.1 ug) as PINK1 negative control.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot detection of murine PINK1 using LS-C2845. 1: molecular weight marker. 2: MES cell Mitochondria (20 ug). 3: MES cytosol (20 ug). 4: MES nuclear (20 ug) as negative control. 5: Purified human cytochrome C (0.1 ug) as PINK1 negative control. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 5/22/2018

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