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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PINK1 Antibody (aa258‑274) LS‑C9809
PINK1 antibody LS-C9809 is an unconjugated rabbit polyclonal antibody to human PINK1. Validated for IHC and WB.
Antibody
Catalog
Size
Price
LS-C9809-100
100 µg
$435

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Product Description

PINK1 antibody LS-C9809 is an unconjugated rabbit polyclonal antibody to human PINK1. Validated for IHC and WB.
About PINK1
Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Q9BXM7 NM_032409 NP_115785.1

PINK1 Antibody, BRPK Antibody, PTEN induced putative kinase 1 Antibody, PARK6 Antibody, PTEN-induced putative kinase Antibody, Protein kinase BRPK Antibody


Specifications

Target
Human PINK1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Dog (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:250 - 1:750)
  • Western blot (1:500 - 1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
PINK1 antibody was raised against residues 258-274 (YRKSKRGPKQLAPHPNI) of human PINK1. Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%); Marmoset, Dog (94%); Bat, Horse (88%); Mouse, Rat, Elephant, Panda, Porcine, Rabbit (82%).
Epitope
aa258-274
Specificity
Reacts with residues 258-274 (YRKSKRGPKQLAPHPNI) of human PINK1.
Usage
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:500-1:1000. Immunohistochemistry: 1:250-1:750.
Presentation
PBS, pH 7.2, 0.1% sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 7/20/2018

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