The Immunohistochemistry Antibody Company
|Human (tested or 100% immunogen sequence identity)|
|Monkey, Dog (at least 90% immunogen sequence identity)|
|PINK1 antibody was raised against synthetic peptide from human PINK1. Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%); Marmoset, Dog (94%); Bat, Horse (88%); Mouse, Rat, Elephant, Panda, Porcine, Rabbit (82%).|
|Residues 258-274 (YRKSKRGPKQLAPHPNI) of human PINK1|
|PBS, 0.02% sodium azide.|
|For research use only.|
PINK1 Antibody, BRPK Antibody, PTEN induced putative kinase 1 Antibody, PARK6 Antibody, PTEN-induced putative kinase Antibody, Protein kinase BRPK AntibodyProtects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.