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Anti-PINK1 Antibody (aa118-147) LS-C99189

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PINK1 Antibodies

Anti-PINK1 Antibody (aa350-500) IHC-plus™ LS-B14185
Rabbit Polyclonal to Human PINK1
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human PINK1
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human PINK1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

  • IHC - Paraffin

Specificity and Use

PINK1 antibody was raised against kLH-conjugated synthetic peptide between amino acids 118-147 from N-terminal region of human PINK1 (PARK6).
LS-E8225 - Lyophilized - 100 µg - $145.00
aa118-147

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About PINK1

Q9BXM7 NM_032409 NP_115785.1

PINK1 Antibody, BRPK Antibody, PTEN induced putative kinase 1 Antibody, PARK6 Antibody, PTEN-induced putative kinase Antibody, Protein kinase BRPK Antibody

Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
Western blot of anti-PARK6 antibody in mouse kidney tissue lysate. PARK6 (arrow) was detected using the purified antibody.

Western blot

Western blot
Western blot of lysate from human placenta tissue, using Park6 (PINK1) Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Western blot

Western blot
Western blot of Park6(PINK1) (arrow) using rabbit polyclonal Park6(PINK1) Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Park6(PINK1) gene.

Western blot

Western blot
Park6 (PINK1) Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The Park6 (PINK1) antibody detected the Park6 (PINK1) protein (arrow).
 

Requested From: United States
Date Requested: 12/11/2016

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