PIF1

PIF1 5'-to-3' DNA helicase

DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.

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Products

Antibodies (15)

Proteins (2)

Type

Over-Expression Lysate (2)

Primary (15)

Target

PIF1 (17)

Reactivity

Human (10)

Mouse (10)

Rat (5)

Application

IHC (7)

IHC-P (6)

WB (6)

ELISA (7)

Peptide-ELISA (1)

Host

rabbit (15)

Isotype

IgG (7)

Clonality

polyclonal pc (15)

Format

Biotin Conjugated (2)

DY488 Conjugated (1)

DY550 Conjugated (1)

DY650 Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (8)

Epitope

Internal (1)

Publications

No (17)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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PIF1 Antibody (Internal) LS-C353552

Antibody:

PIF1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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PIF1 Antibody LS-C150731

Antibody:

PIF1 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$386

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PIF1 Antibody (Biotin) LS-C181948

Antibody:

PIF1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P

Format:

Biotin Conjugated

Price:

0.1 ml/$416

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PIF1 Antibody (DY650) LS-C181949

Antibody:

PIF1 Rabbit anti-Human Polyclonal (DY650) Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P

Format:

DY650 Conjugated

Price:

0.1 ml/$416

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PIF1 Antibody (DY550) LS-C181952

Antibody:

PIF1 Rabbit anti-Human Polyclonal (DY550) Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P

Format:

DY550 Conjugated

Price:

0.1 ml/$416

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PIF1 Antibody (DY488) LS-C181950

Antibody:

PIF1 Rabbit anti-Human Polyclonal (DY488) Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P

Format:

DY488 Conjugated

Price:

0.1 ml/$416

• Unconjugated
• Biotin
• DY650
• DY550
• DY488

• Unconjugated
• Biotin
• DY650
• More...
  • DY550
  • DY488

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PIF1 Antibody LS-C679027

Antibody:

PIF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PIF1 Antibody (HRP) LS-C679028

Antibody:

PIF1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

PIF1 Antibody (Biotin) LS-C679026

Antibody:

PIF1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

PIF1 Antibody (FITC) LS-C679029

Antibody:

PIF1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PIF1 Antibody LS-C807784

Antibody:

PIF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PIF1 Antibody LS-C769635

Antibody:

PIF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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PIF1 Antibody LS-C754269

Antibody:

PIF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

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PIF1 Antibody LS-C780965

Antibody:

PIF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

PIF1 Antibody LS-C342130

Antibody:

PIF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

PIF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109618

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.6 kDa

Price:

100 µg/$710

Select

Human PIF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91902

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.6 kDa

Price:

20 µg/$215

Viewing 1-17 of 17 product results

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