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Anti-PIAS4 / PIASY Antibody (N-Terminus) LS-C108719

Catalog Size Price
LS-C108719-100 100 µg (1 mg/ml) Unavailable

Related Products

37 PIAS4 / PIASY Antibodies

Most Popular PIAS4 / PIASY Antibodies

Anti-PIAS4 / PIASY Antibody (aa48-79) LS-C98800
Rabbit Polyclonal to Human PIAS4 / PIASY
Human
IHC, IHC - Paraffin, Western blot
Unconjugated
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Anti-PIAS4 / PIASY Antibody (N-Terminus) LS-C108719
Rabbit Polyclonal (IgG) to Human PIAS4 / PIASY
Human, Mouse, Rat
Western blot, ELISA
Unconjugated
Immunohistochemistry of PIAS4 in rat brain tissue with PIAS4 antibody at 5 µg/mL.
Anti-PIAS4 / PIASY Antibody (aa451-500) IHC-plus™ LS-B7648
Rabbit Polyclonal (IgG) to Human PIAS4 / PIASY
Human, Mouse
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Unconjugated
Anti-PIAS4 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7648 dilution 1:100.
Anti-PIAS4 / PIASY Antibody (aa48-79) LS-C324025
Rabbit Polyclonal (IgG) to Human PIAS4 / PIASY
Human
IHC, Western blot, ELISA
Unconjugated
Anti-PIAS4 / PIASY Antibody (aa471-499) LS-C328130
Rabbit Polyclonal (IgG) to Human PIAS4 / PIASY
Human
IHC, Western blot, ELISA
Unconjugated

100% Guaranteed Publications (2)
Rabbit Polyclonal (IgG) to Human PIAS4 / PIASY
Human, Mouse, Rat
Western blot, ELISA
Unconjugated

Details

Human PIAS4 / PIASY
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1 - 2 µg/ml)
  • ELISA

  • IHC - Paraffin

Specificity and Use

LS-E30924 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-C108719. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
N-Terminus
PIAS4 antibody can be used for detection of PIAS4 by Western blot at 1-2 ug/ml.

Packaging

PBS, 0.02% sodium azide
Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.
For research use only.

Publications (2)

1
Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response. Conn KL, Wasson P, McFarlane S, Tong L, Brown JR, Grant KG, Domingues P, Boutell C. Journal of virology. 2016 90:4807-26. (ICC, WB; Human) [Full Text Article] [PubMed:26937035] [PMC:PMC4836348]
2
SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1. Brown JR, Conn KL, Wasson P, Charman M, Tong L, Grant K, McFarlane S, Boutell C. Journal of virology. 2016 90:5939-52. (ICC, WB; Human) [Full Text Article] [PubMed:27099310] [PMC:PMC4907222]

About PIAS4 / PIASY

Q8N2W9 NM_015897 NP_056981.2

PIAS4 Antibody, E3 SUMO-protein ligase PIAS4 Antibody, PIAS-gamma Antibody, ZMIZ6 Antibody, Piasg Antibody, PIASY Antibody

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168.

Immunohistochemistry

Immunohistochemistry of PIAS4 in rat brain tissue with PIAS4 antibody at 5 µg/mL.
Immunohistochemistry of PIAS4 in rat brain tissue with PIAS4 antibody at 5 µg/mL.

Western blot

Western blot analysis of PIAS4 in HL60 cell lysate with PIAS4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Western blot analysis of PIAS4 in HL60 cell lysate with PIAS4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.

Western blot

Western blot of PIAS4 in rat brain tissue lysate with PIAS4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Western blot of PIAS4 in rat brain tissue lysate with PIAS4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Requested From: 
Date Requested: 5/21/2018

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