Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
Gene Name: | phosphatidylinositol 4-kinase type 2 beta |
Family/Subfamily: | Non-Protein Kinase |
Synonyms: | PI4K2B, PI4KIIB, PIK42B, PI4KII-BETA |
Target Sequences: | NM_018323 NP_060793.2 Q8TCG2 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.