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Anti-PHLPP2 / PHLPPL Antibody (C-Terminus) IHC-plus™ LS-B8861

Note: This antibody replaces LS-C153646

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

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Orders@LSBio.com
 

Most Popular PHLPP2 / PHLPPL Antibodies

Anti-PHLPP2 / PHLPPL Antibody (C-Terminus) IHC-plus™ LS-B6340
Rabbit Polyclonal (IgG) to Human PHLPP2 / PHLPPL
Human, Mouse
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-PHLPP2 / PHLPPL Antibody (C-Terminus) IHC-plus™ LS-B8861
Rabbit Polyclonal to Human PHLPP2 / PHLPPL
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human PHLPP2 / PHLPPL
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human PHLPP2 / PHLPPL
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (2.5 µg/ml)
  • Western blot (1 - 2 µg/ml)

Specificity and Use

PHLPP2 / PHLPPL antibody was raised against a 20 amino acid peptide near the carboxy terminus of human PHLPP2.
LS-E31328 - Liquid - 50 µg - $145.00
C-Terminus
Human PHLPP2. At least three isoforms are known to exist; this antibody will detect the two largest isoforms. PHLPP2 antibody is predicted to not cross react with PHLPP1.
PHLPP2 antibody can be used for detection of PHLPP2 by Western blot at 1-2 ug/mL.

Packaging

PBS, 0.02% sodium azide
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About PHLPP2 / PHLPPL

Q6ZVD8 NM_015020 NP_055835.2

PHLPP2 Antibody, PHLPPL Antibody, PHLPP-like Antibody, KIAA0931 Antibody

Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser-657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3.

Immunohistochemistry

Immunohistochemistry
Anti-PHLPP2 / PHLPPL antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunocytochemistry

Immunocytochemistry
Immunocytochemistry of PHLPP2 in SW480 cells with PHLPP2 antibody at 2.5 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of PHLPP2 in SW480 cells with PHLPP2 antibody at 5 ug/ml.

Western blot

Western blot
Western blot analysis of PHLPP2 in SW480 cell lysate with PHLPP2 antibody at 1 ug/ml in (A) the presence and (B) the absence of blocking peptide.

Requested From: United States
Date Requested: 12/2/2016

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