Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 4E9] (IgG2a) to Human PGAM2
Human, Monkey, Mouse
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Rabbit Polyclonal (IgG) to Human PGAM2
ICC, Western blot
Human (tested or 100% immunogen sequence identity)
Mouse, Rat, Bovine, Pig (at least 90% immunogen sequence identity)
ICC (1:100 - 1:1000)
Western blot (1:5000 - 1:20000)
Specificity and Use
PGAM2 antibody was raised against recombinant fragment corresponding to a region within amino acids 1 and 253 of PGAM2 (SwissProt P15259). Percent identity by BLAST analysis: Human (100%); Pig (96%); Bovine (94%); Rat (93%); Mouse (92%).
0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.