Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
PEBP1 / RKIP antibody was raised against synthetic peptide derived from the N-terminal region of human RKIP (Raf kinase inhibitor protein).
Reacts with human and mouse RKIP. In Western Blots, identifies a single 23kD band. Reactivity has been confirmed with human HEK293 cell lysates and mouse brain homogenates. Based on amino acid sequence homology, expected to react with bovine and monkey RKIP.
Suitable for use in ELISA, Western Blot. ELISA: 0.1-1.0 ug/ml. Western Blot: 1-3 ug/ml.
PBS, pH 7.4, 0.05% sodium azide.
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
PEBP1 Antibody, HCNP Antibody, HCNPpp Antibody, PBP Antibody, Prostatic binding protein Antibody, Raf kinase inhibitor protein Antibody, Raf kinase inhibitory protein Antibody, Prostatic-binding protein Antibody, Neuropolypeptide h3 Antibody, PEBP Antibody, PEBP-1 Antibody, RKIP Antibody
Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.