Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
PDLIM5 / LIM antibody was raised against synthetic peptide derived from the N-terminal region of the human ENH (enigma homologue 1, LIM protein, protein kinase C- binding protein enigma) protein, which differs from mouse and rat ENH by one amino acid.
Recognizes human ENH proteins. Reactivity has been confirmed with human PC-3, LNCap-FGC, Caco-2, and HT-29 cell lysates, mouse heart and skeletal muscle homogenates and rat heart homogenates.
Suitable for use in Western Blot. Western Blot: 1-3 ug/ml; Target band at ~65kD.
PBS, pH 7.4, 0.1% Sodium Azide
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses.