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PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene Name: | phosphodiesterase 4C, cAMP-specific |
Family/Subfamily: | Phosphodiesterase , PDE - cAMP-specific |
Synonyms: | PDE4C, DPDE1, Pde-ivc, PDE21, Phosphodiesterase 4c, Pde4c2 |
Target Sequences: | NM_000923 AAD47053.1 Q08493 |
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