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Anti-PDE2A Antibody (C-Terminus) LS-C82363

Ordering

Wt. Vol. Conc. Price
- 50 µl - Unavailable

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Rabbit Polyclonal to Human PDE2A
Human, Mouse, Rat
IHC, Western blot, Immunoprecipitation
Unconjugated

Details

Human PDE2A
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • IHC
  • Western blot (1:2000)
  • Immunoprecipitation

Specificity and Use

PDE2A antibody was raised against designed from the C-terminal region common to all known 2A isoforms.
C-Terminus
The antibody selectively detects proteins corresponding to members of the PDE2A sub-family in human samples.
Predicted cross-reactivity with mouse and rat is based solely on sequence homology. The antibody has not been tested using mouse or rat samples at this time. Please also note that antibody works best with transfected cell lysates as observed on the WB image.

Packaging

Diluted antiserum.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About PDE2A

O00408 NM_002599 NP_002590.1

PDE2A Antibody, CGMP-stimulated PDE Antibody, Cyclic GMP-stimulated PDE Antibody, PDE2 Antibody, Pde2a2 Antibody, PED2A4 Antibody, Phosphodiesterase 2A Antibody, CGS-PDE Antibody, CGSPDE Antibody, PDE2A1 Antibody, Pde2a3 Antibody

Phosphodiesterase 2A is a cGMP stimulated, cAMP/cGMP dual-specific phosphodiesterase whose hydrolytic activity is stimulated by the presence of cGMP binding to the GAF domain. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transit across the endothelial cell barrier (i. e., venous and capillary). PDE2A activity is inhibited by erythro-9-(2-hydroxyl-3-nonyl)adenine (EHNA).

Western blot

Western blot
Western blot of PDE2A antibody (1:2,000) against lysate from COS cells transfected with the indicated human PDE isoform.

Western blot

Western blot
Western blot of PDE2A antibody (1:2000) against lysate from COS cells transfected with the indicated human PDE isoform.

Requested From: 
Date Requested: 4/25/2017

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