Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 8G8] (IgG1) to Human PDCD1LG2 / CD273 / PD-L2
IHC, IHC - Paraffin, Western blot
Mouse Monoclonal (IgG1) to Human PDCD1LG2 / CD273 / PD-L2
Human PDCD1LG2 / CD273 / PD-L2
Human (tested or 100% immunogen sequence identity)
Protein G purified
Specificity and Use
Human B7-DC transfected ul cells.
Recognizes human CD273.
Suitable for use in Flow cytometry. Flow Cytometry: Neat Use 10 ul of the suggested working dilution to label 1x1E6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Lyophilized powder from PBS, pH 7.4, 0.09% sodium azide, 1% BSA. Reconstitute, 1 ml sterile ddH2O, 40-50% glycerol.
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.