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Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (clone MIH14) LS-C58206

Note: This antibody replaces LS-C58205

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $270
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PDCD1LG2 / CD273 / PD-L2 Antibodies

Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (clone 8G8) LS-C340014
Mouse Monoclonal [clone 8G8] (IgG1) to Human PDCD1LG2 / CD273 / PD-L2
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (FITC) LS-C128028
Mouse Monoclonal (IgG1) to Human PDCD1LG2 / CD273 / PD-L2
Human
Flow Cytometry
FITC Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone MIH14] (IgG1) to Human PDCD1LG2 / CD273 / PD-L2
Human
IHC - Frozen, Flow Cytometry (applications tested for the base form of this product only)
Unconjugated

Details

Human PDCD1LG2 / CD273 / PD-L2
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MIH14]
Unconjugated. Also available conjugated with RPE, FITC.
Affinity purified
Unmodified

Applications

  • IHC - Frozen
  • Flow Cytometry (1:10 - 1:50)
  • (applications tested for the base form of this product only)

Specificity and Use

PDCD1LG2 / CD273 / PD-L2 antibody was raised against human B7-DC transfected L cells.
Detects human CD273, also known as B7-DC and Programmed Death Ligand 2 (PD-L2). CD273 is a 42kD member of the immunoglobulin receptor superfamily, and is a ligand for CD279 (PD-1). CD273 is primarily expressed on dendritic cells, and its expression can be induced on inflammatory macrophages when activated by interleukin 4 or Th2 cells. CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, and is particularly important in the maintenance of self tolerance.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About PDCD1LG2 / CD273 / PD-L2

Q9BQ51 NM_025239 NP_079515.2

PDCD1LG2 Antibody, B7 dendritic cell molecule Antibody, B7-DC Antibody, B7DC Antibody, BA574F11.2 Antibody, CD273 Antibody, Btdc Antibody, CD273 antigen Antibody, PD-L2 Antibody, PDCD1 ligand 2 Antibody, PD-1-ligand 2 Antibody, Programmed death ligand 2 Antibody, Butyrophilin B7-DC Antibody, PD-1 ligand 2 Antibody, PDCD1L2 Antibody, PDL2 Antibody

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Requested From: United States
Date Requested: 12/7/2016

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